Cancer Cell Dissemination During Surgical Manipulation
نویسندگان
چکیده
منابع مشابه
Tumor cell dissemination secondary to surgical interventions in the breast.
Dissemination secondary to surgical interventions is an issue that arises in conversations between patients and providers prior to breast biopsy. Research supports needle biopsies over incisional or excisional biopsies in most situations. Tumor cell dissemination is a rare occurrence. However, the fear of dissemination as experienced by the patient is very real. That fear may influence the pati...
متن کاملTransbronchial Dissemination of Squamous Cell Lung Cancer
We report a case of squamous cell lung cancer with transbronchial dissemination in a 73-year-old man. Bronchoscopic examination revealed multiple bronchial mucosal nodules that existed independently of one another. We reviewed 16 previous cases of endobronchial metastasis in lung cancer. All patients were men. Among the reports that described the smoking history, most patients were smokers (6/7...
متن کاملExpression of β-globin by cancer cells promotes cell survival during blood-borne dissemination
Metastasis-competent circulating tumour cells (CTCs) experience oxidative stress in the bloodstream, but their survival mechanisms are not well defined. Here, comparing single-cell RNA-Seq profiles of CTCs from breast, prostate and lung cancers, we observe consistent induction of β-globin (HBB), but not its partner α-globin (HBA). The tumour-specific origin of HBB is confirmed by sequence polym...
متن کاملCCR7: roles in cancer cell dissemination, migration and metastasis formation.
The CC-chemokine receptor 7 (CCR7) coordinates the migration of cancer cells as well as immune cells towards lymphatic organs where its two ligands CCL19 and CCL21 are constitutively expressed. Here we provide a topological model of CCR7, which belongs to the class A of G-protein coupled, seven-transmembrane spanning receptors, and describe how CCR7 expression is regulated. We focus on its role...
متن کاملTumor-infiltrating granulocytic cells promote cancer cell dissemination
Most studies aimed at understanding the link between inflammation and cancer progression have focused on macrophages. In a recent study published in PLoS Biology, Toh B et al (2011) Mesenchymal transition and dissemination of cancer cells is driven by myeloid-derived suppressor cells infiltrating the primary tumorPLoS Biol9 e1001162, we show that a subset of granulocytic cells already known to ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: The Tohoku Journal of Experimental Medicine
سال: 1963
ISSN: 0040-8727,1349-3329
DOI: 10.1620/tjem.79.319